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Bang, Jan Holm, Tage L. We studied the 24 h urinary excretion of albumin, transferrin, immunoglobulin G, and retinol-binding protein in individuals with essential hypertension, white coat hypertension, and Naeztved. In 56 individuals, we measured the 24 h ambulatory blood pressure AMBP.
The individuals could Naestved white legal high divided into Free adult dating site Roskilde groups: We determined with immunochemical methods the 24 h urinary excretions of albumin, transferrin, and immunoglobulin G, all markers of glomerular dysfunction, and retinol-binding protein, a marker of impaired proximal tubular function.
Two cases of microalbuminuria were found among the 14 white coat hypertensives. Immunoglobulin G excretion was not significantly increased in any of the hypertensive groups. In hypertensives, a significant correlation was found between urinary excretion of albumin and transferrin and office blood pressure and systolic AMBP.
There was no significant correlation between the urinary excretions of IgG and retinol-binding protein and legak pressures in any of the three groups.
Our findings indicate that dhite with white coat hypertension, like hypertensives, have a selective type of glomerular dysfunction. However, proximal tubular dysfunction was seen only in hypertensives. Urinary excretions of albumin, transferrin, and retinol-binding protein may be useful as markers of glomerular and tubular dysfunction in essential hypertension.
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Article Contents. Address correspondence and reprint requests to Lia E. Oxford Academic. Google Scholar. Jan Holm.